Titia de Lange gives an overview of telomeres, the protective repeats at the ends of chromosomes, and discusses the proteins that protect telomeres, how telomeres are maintained by telomerase, the mechanisms of telomere shortening, and the role of telomere shortening in cancer and several inherited human diseases.

Visit iBiology to view more seminars and short talks on science topics. iBiology was founded in 2006 by Lasker laureate Ron Vale.

Part One: Telomeres and human disease

Part Two: How telomeres solve the end-protection problem