In this issue, Leroy Hood details his trailblazing career across diverse scientific fields, and Solomon Snyder talks about his discovery of the first neurotransmitter receptors in the brain. We also feature the final installments of our video interview with Nancy Wexler.

Leroy Hood: Leading the systems biology revolution
A pioneer of systems biology, Hood is dedicated to developing new technologies and approaches to tackle complex biological questions.

Solomon Snyder: Defining how the brain responds to opioids
Snyder’s discovery of opiate receptors opened the field of neurotransmitter-synaptic interactions.

An Interview with Nancy Wexler: Chapters 5, 6, and 7
In these three final chapters, Wexler discusses the ethical implications of genetic research, her experience winning the 1993 Lasker Award, and the future of Huntington’s disease research.