Albert Lasker
Basic Medical Research Award

Key Publications of Richard H. Scheller

Trimble, W.S., Cowan, D.M., and Scheller, R.H. (1988). VAMP-1: A synaptic vesicle-associated integral membrane protein. Proc. Natl. Acad. Sci. USA. 85, 4538-4542.

Bennett, M.K., Calakos, N., and Scheller, R.H. (1992). Syntaxin: A synaptic protein implicated in docking of synaptic vesicles at presynaptic active zones. Science. 257, 255-259.

Söllner, T., Bennett, M.K., Whiteheart, S.W., Scheller, R.H., and Rothman, J.E. (1993). A protein assembly-disassembly pathway in vitro that may correspond to sequential steps of synaptic vesicle docking, activation, and fusion. Cell. 75, 409–418.

Calakos, N., Bennett, M.K., Peterson, K.E., and Scheller, R.H. (1994). Protein-protein interactions contributing to the specificity of intracellular vesicular trafficking. Science. 263, 1146-1149.

Lin, R.C. and Scheller, R.H. (1997). Structural organization of the synaptic exocytosis core complex. Neuron. 19, 1087-1094.

Chen, Y.A., Scales, S.J., Patel, S.M., Doung, Y.-C., and Scheller, R.H. (1999). SNARE complex formation is triggered by Ca2+ and drives membrane fusion. Cell. 97, 165-174.

Review Articles by Scheller and Südhof on Neurotransmitter Release
Bennett, M.K. and Scheller, R.H. (1993). The molecular machinery for secretion is conserved from yeast to neurons. Proc. Natl. Acad. Sci. USA. 90: 2559-2563.

Südhof, T.C. (1995). The synaptic vesicle cycle: A cascade of protein-protein interactions. Nature. 375, 645-653.

Lin, R.C. and Scheller, R.H. (2000). Mechanisms of synaptic vesicle exocytosis. Annu. Rev. Cell Dev. Biol. 16, 19-49.

Südhof, T.C. (2012). Calcium control of neurotransmitter release. Cold Spring Harb. Perspect. Biol. 4:a011353, 1-15.