Albert Lasker
Clinical Medical Research Award

Brennan, F.M., Chantry, D., Jackson, A., Maini, R.N., Feldmann, M. (1989) Inhibitory effect of TNF alpha antibodies on synovial cell interleukin-1 production in rheumatoid arthritis. Lancet 2: 244–247.

Chu C.Q., Field, M., Feldmann, M., Maini, R.N. (1991) Localization of tumor necrosis factor alpha in synovial tissues and at the cartilage-pannus junction in patients with rheumatoid arthritis. Arthritis Rheum. 34: 1125–1132.

Williams, R.O., Feldmann, M., Maini, R.N. (1992) Anti-tumor necrosis factor ameliorates joint disease in murine collagen-induced arthritis. Proc. Nat. Acad. Sci. 89: 9784–9788.

Elliott, M.J., Maini, R.N., Feldmann, M., Kalden, J.R., Antoni, C., Smolen, J.S., Leeb, B., Breedveld, F.C., Macfarlane, J.D., Bijl, H., Woody, J.N. (1994) Randomised double-blind comparison of chimeric monoclonal antibody to tumour necrosis factor alpha versus placebo in rheumatoid arthritis. Lancet 344: 1105–1110.

Maini, R.N., Breedveld, F.C., Kalden, J.R., Smolen, J.S., Davis, D., Macfarlane, J.D., Antoni, C., Leeb, B., Elliott, M.J., Woody, J.N., Schaible, T.F. Feldmann, M. (1998) Therapeutic efficacy of multiple intravenous infusions of anti-tumor necrosis factor alpha monoclonal antibody combined with low-dose weekly methotrexate in rheumatoid arthritis. Arthritis Rheum. 41: 1552–1563.

Feldmann, M., Maini, R.N. (2001) Anti-TNF-alpha therapy of rheumatoid arthritis: what have we learned? Annu. Rev. Immunol. 19: 163–196.