Albert Lasker
Basic Medical Research Award

Key Publications by Mario Capecchi

Capecchi, M.R. (1980) High efficiency transformation by direct microinjection of DNA into cultured mammalian cells. Cell 22: 479–488.

Folger, K.R., Wong, E.A., Wahl, G. and Capecchi, M.R. (1982) Patterns of integration of DNA microinjected into cultured mammalian cells: Evidence for homologous recombination between injected plasmid DNA molecules. Mol. Cell. Biol. 2: 1372–1387.

Thomas, K.R., Folger, K.R. and Capecchi, M.R. (1986) High frequency targeting of genes to specific sites in the mammalian genome. Cell 44: 419-428.

Thomas, K.R., Capecchi, M.R. (1987) Site-directed mutagenesis by gene targeting in mouse embryo-derived stem cells. Cell 51: 503–512.

Mansour, S.L., Thomas, K.R., and Capecchi, M.R. (1988) Disruption of the proto-oncogene int-2 in mouse embryo-derived stem cells: A general strategy for targeting mutations to nonselectable genes. Nature 336: 348–352.

Capecchi, M.R. (1994) Targeted gene replacement. Sci. Am. 270: 54–61.

Capecchi, M.R. (1995) A personal view of gene targeting. Accomplishments in Cancer Research 1994. (J.G. Fortner and J.E. Rhoads, Ed.) Philadelphia: J.B. Lippincott, pp. 67–68.