Albert Lasker
Basic Medical Research Award

Ciechanover, A., Hod, Y., and Hershko, A. (1978) A heat-stable polypeptide component of an ATP-dependent proteolytic system from reticulocytes. Biochem. Biophys. Res. Commun. 81: 1100–1105.

Hershko, A., Ciechanover, A., Heller, H., Haas, A. L., and Rose, I. A. (1980) Proposed role of ATP in protein breakdown: conjugation of proteins with multiple chains of the polypeptide of ATP-dependent proteolysis. Proc. Natl. Acad. Sci. USA 77: 1783–1786.

Ciechanover, A., Elias, S., Heller, H. and Hershko, A. (1982) Covalent affinity purification of I ubiquitin-activating enzyme. J. Biol. Chem. 257: 2537–2542.

Hershko, A., Heller, H., Elias, S. and Ciechanover, A. (1983) Components of ubiquitin-protein ligase system: resolution, affinity purification, and role in protein breakdown. J. Biol. Chem. 258: 8206–8214.

Finley, D., Ciechanover, A. and Varshavsky, A. (1984) Thermolability of ubiquitin-activating enzyme from the mammalian cell cycle mutant ts85. Cell 37: 43–55.

Ciechanover, A., Finley, D. and Varshavsky, A. (1984) Ubiquitin dependence of selective protein degradation demonstrated in the mammalian cell cycle mutant ts85. Cell 37: 57–66.

Ferber, S. and Ciechanover, A. (1987) Role of Arginine-tRNA in Protein Degradation by the Ubiquitin Pathway. Nature 326: 808–811.

Ciechanover, A., Ferber, S., Ganoth, D., Elias, S., Hershko, A. and Arfin, S. (1988) Purification and characterization of arginyl-tRNA-protein transferase from rabbit reticulocytes: its involvement in modification and ubiquitin-dependent degradation of proteins bearing acidic N-termini. J. Biol. Chem. 263: 11155–11167.