Albert Lasker
Basic Medical Research Award

Key Publications by Roderick MacKinnon

MacKinnon, R. (1991) Determination of the subunit stoichiometry of a voltage-dependent potassium channel. Nature 350: 232–235.

Heginbotham, L., Abramson, T., MacKinnon, R. (1992) A functional connection between the pores of distantly related ion channels as revealed by mutant K+ channels. Science 258: 1152–1155.

Root, M.J. and MacKinnon, R. (1994) Two identical noninteracting sites in an ion channel revealed by proton transfer. Science 265: 1852–1856.

Hidalgo, P. and MacKinnon, R. (1995) Revealing the architecture of a K+ channel pore through mutant cycles with a peptide inhibitor. Science 268: 307–310.

Doyle, D.A., Cabral, J.M., Pfuetzner, R.A., Kuo, A., Gulbis, J.M., Cohen, S.L., Chait, B.T., MacKinnon, R. (1998) The structure of the potassium channel: molecular basis of K+ conduction and selectivity. Science 280: 69–77.

MacKinnon, R., Cohen, S.L., Kuo, A., Lee, A., Chait, B.T. (1998) Structural conservation in prokaryotic and eukaryotic potassium channels. Science 280: 106–109.